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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3018f9e6dba253dfc33863f997093e3057663a10b8d6522e85e50451e39c9df' 
  AND token = '+ICnVXZddynf9G77uhPS9EkLqquEGh2QKm+q+Qx2jIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}