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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec2c818c835850254f89e22a380d88a8a1d9cc8b90840d01e84c0fe985f4dda' 
  AND token = 'O4D/NQFvkPhT0/yDH1stS4fmIzsacPi36g9CEIoaDyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}