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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cefa14fb76797785547886007346b4e51bd59d6f2d68b230d40177a81be42795' 
  AND token = 'QxsLDd/4O5/n9DdjqA8tLh2rU9917eUS5IAyAsYI3rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}