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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '240abd6d4ab45edeccba075504e46f5b12635d8726cde396f7a7c522abbddaad' 
  AND token = '2Q4SB6eXhwdTky+e50jF9/VK42k/Qk7LAMKeRMhMclI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}