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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e522d383e4aba3ce82de7c2c36429c490aaaf2ef3f71753852ace9039067b67' 
  AND token = 'Ee4eKFTjBU6hLhq4nNJqxI5kXUEX0iRG4JnxgG/6EY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}