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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c2996a53b49e217e19195bbf83524deb25f0533a469e7f41ddc555ea32bc89' 
  AND token = 'mYonr/ibfkHrBDrdz+CAi/4ghK7R1qyuEuKhPz+ToeI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}