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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62b1176737f3e93c7d9c2686148096e490266d9908652c43abf30382f364bc2' 
  AND token = 'Oc1AN7GBpX7/gdBCSNBY9gmOyIxD0NRED0Bf2nBjP1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}