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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef80509b72cd2db478b8af3b51d89a8660d09ef90115729071297edd75c36524' 
  AND token = 'MOoWlxdq2xxAjMxDHt06eAhpxCN2xOYTvr7W/RLXdvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}