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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e46f411a1c2124b8196c8790baee8f3602e595202d1e2dd67638be1fdcb2fa5f' 
  AND token = '0V13qocJhW9jfMev71hVeR5eKCKHz5014WXBeimQYGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}