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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be06d027ca28fbad1275c30d7a15b7743276d4cdcd7dafb45797e869f59e1144' 
  AND token = 'dwi2gQSnnza95G/qSdYHyTzgXrgP7ZxdcQXwpiRSZjg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}