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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3105ec655635e71b97ef85bd3128c83d2b8007912201d12322af05336a74b26' 
  AND token = 'n2F4h20sw9ECOBonnxDy+rtx1MN9rKF+j06ORdUF3oU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}