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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cafe2d9d1d3f198056ae175d3d86482a68a033a74ae66b831036157480545338' 
  AND token = 'gfDx+TvFGJC+VidwEa5mov2BXEsrrhK5BAdTRIt8qOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}