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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '497c558d99bb9e2e0cf55c1e0c0517c5d8a614535d68b0faa81851007a4a93a9' 
  AND token = 'xYZiAq5XP5JLWvLgnOtDlZhjpvOcOu6xUFahkRTHdLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}