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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bbc38d328e107e2ef0bbd9046ce32d0b95fafa75dc42a4e7be8b42fd03b247b' 
  AND token = 'wU4RddoMkl1/jgkE6qtkFmM9JMGJNNiwNLEVMMmGS3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}