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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006ab206788c2d0b54e86aab51049bbb4f1efd3b22c952dc72b022b29b6feae6' 
  AND token = 'H3eQvZ2X14yhtwvBypqlZhiIEm9DtqRAwGJiX17XJDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}