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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e55c976918b596f1a6016b384630acb9d341e742e7345b0cb4a3c16a45f93bf' 
  AND token = 'jMflx3EQCKgNOPXx4OekUQtTr/fvubkG6UaF/NhlVaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}