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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a315280dc7987efa1298676537b3e23e8ff2066338dc9a19235e4f2db4072046' 
  AND token = 'qk7mCTkqWiTReF+dCA243VbywX7wb9G36RdFurrrr44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}