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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b53767866041c8c6cc38a5d71b89e07cbe1d9df2d45bf38535d1499a50952b3' 
  AND token = 'XX3xkdsYx896qLIcgZL4+dbp0q8jlX2qoRu88OnREek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}