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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66579bcf7835dc9ae5409b625bdd66b9476629d4b25c4fca23dd763fa6911f0e' 
  AND token = 'fV2IWQGdg2N/Kv9aem0w5jnIoiG7ke7PsARbnjNyk3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}