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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75a5229417ee9797dda526c7b588806cc25e8f6411d78181c9808236f9567998' 
  AND token = 'FgxvYwvrzveU8tXu7eB8zumU8Ckc0bxYCIjjCCu0mFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}