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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a111743a7e22b5e67c864c1947b898335dc43d092204a893550bd8bdbf2040fe' 
  AND token = 'PPJIGhM1Gdu2UJYsRyT6b8BA8B8Ni3gPPOlN3twJvls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}