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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f69a457c647b34941cc470b55c994e6fbe34aaf0ba78330d8648fe313ae9db6' 
  AND token = 'CKIPqTozy7j8EtDzfLh8vHimJIQ355w0EBBwBZ0njJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}