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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c0af5379721840e19d26894c93773958db7206c366d62b8be644d102f1708da' 
  AND token = '1nJLg0pSLx3++N1yAoi6B5yde7rjcM2bPkIPgPFyV9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}