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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66f7373a0763cbfb1456325231f58d4b0c58c547bf6ab181833e94379ebe1746' 
  AND token = '2lX1u2bHXZzyfPAVMV6/0Dg1auKTOaPYXwAGlxE7pAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}