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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d63d817db86b98bee33401ff0ceedde443884328b9dcd1f6454cd0a15a4ed3' 
  AND token = 'iN+j4gU++JhfuzbNF7HUmR6g3MIfokbN9fAWYHLtUAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}