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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a09e869c5fdba597087892b0a02e4deb089602cdd2878ff6eea0e3a7f3776040' 
  AND token = '2RCOu/DdkfTTjob9oEdCS1jgrFyX2+nIQikjcLXFQFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}