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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3375995bfb7eb5bafb196f7d582435d865f46b0e48b5042da8c27a8edec7339b' 
  AND token = 'kVOJ+qVthfvWQFVBf6acq5QvU1tT9Ut3iIiU8HgbUXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}