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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '211065f7ff6b46b2f175bf17feca164ac372c0ab6900233dcd51538ed0f2ab3a' 
  AND token = 'i/J6TD+WOw7uHd1XLn9RxYksiJ6epmmpf6qdybK3Tww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}