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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d9ee1dc9cff6fd5d232d0294900ea347e6e77910291090b9439079773e0f87' 
  AND token = 'BnchA2IWEn9GY7BvSbO8OoBD+C0WUbMbn9a8dOzwK4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}