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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221ed137ff082d6ed31a8e136e14ff5f393a5778296ff9194e906cc17149f216' 
  AND token = 'x0wlycY6Iax1nmFmWksdAwfJFcTb1GRx/or1wgO1030=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}