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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15b6d49ac0aa56032da9866fc0f22776563ff9c21aab0a5a76d5401f36da6e96' 
  AND token = 'CNcimE1T0mOAt9sfipK6B1QNYmTWEsdp1sQYhGAEjXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}