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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a92e0b9eb98cfeab0784969b9f4e3573d4c997c8d97c66f644f53feb6587e63' 
  AND token = '+wS1nGBmEVUSBkyxEOPxPsiWRdj3R2D83nce05hc6sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}