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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54a5e7f56e8deafb4260dbbe2f976bbaf9856c00db5f78e247e8d876c972f49b' 
  AND token = 'M1UoF93vQ6/9N9Z6EvM0SZ+7Zx4Y5ga7+aYfsIyaZuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}