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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644899ce805d0f0ee46f30b89d0f987282def6a71f5d6b5c5b37915c15901a0d' 
  AND token = 'a8nz+Pfyc/zxYzG1chEZMoK+50KNEsiyAdEKh/IpUhg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}