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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bf68f780336547819802059f167f701e44c23ce8b7405169e328448490454c6d' 
  AND token = '12lErP/oWip4AD6Iwd3PUOX3yU48nkeqr047fA+yezY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}