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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2e17fccd459aa96690e46f110e642dd347e16f0b8abd779c76b5e472e11f2d7' 
  AND token = 'ZaTYRj7XK+l3xlDTV/DP6Fyi5tFUanTosKsuY88MBHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}