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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7876e73aac6e985c2fabfb3fb1905b3cf7ca84c728d2969a01aa78a8b86d6d5f' 
  AND token = '4rjlVbd7ZERNr4iQv5nYnuDe5wkAnwiS7zwEWif0yPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}