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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '844207f58f7ae1c9d52be1db9ee981b788e4929a96a3c8294466b117b5168d49' 
  AND token = 'WguVP2BusVoLUy6wub3SwGGjYHLwGmjdslIc858Hyw8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}