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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6880d82b4d89c5f9c9abbb6c6040927a3f4dd677f5d54dea073c7af974e40721' 
  AND token = 'z8xB0ekFOsYZfXc/b0SMaKlv7y4bazGx+94z22jm1IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}