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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8072951f45b9a116f97aa3e8519ba32a9c1aa4c045b43513558bcf0aa867fd5d' 
  AND token = 'I5Z12Jq40vEb7chRJNqzXh0DM5W2ybahGrToz/nnjS8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}