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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db12d287221d3441a9a87a073c7d5ce8e45d767a2769a7efa824db301cd2c087' 
  AND token = '+JO/Esp4apC/BAP/f2OOsJmNdQuIkhoIY2eJyK0GOc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}