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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfaf72b1e10997f614291c53d4459c378ba93f01941ced77c3c2841141e1dd4' 
  AND token = 'D8X2CzeJsWwaPbVvlRuMhdm3udfC/3V43bGqbOSWAe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}