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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed9785436874f33522de915aec23957eed4934fe9055b52c7a6403b8abac9ea1' 
  AND token = 'k7m/7gIACOOvc5uJ43hGvLHYXN/yYlVY/rwRRVRgdcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}