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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ef60ba50d5e2c42eca9a9bb23b9170e7a13d865d36d5c7c9bc7e7ee974a1f1' 
  AND token = 'Pp+uI8HfQTU/IRsFUYeCSCd8qCmK2L1sjiaFyjcqkTI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}