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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4abe23c4ff3dbea3d8064b85f744d6c1f64d99bb510f43c58f4ea10e944fd01' 
  AND token = 'eMbiWHTjuQgW1wtIZX8+xilE7MZ9xMw5nXr790lkZG8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}