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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7dfdfc93d35a050e467d112a3cabd8c55bd5ebe944b0b377e078f2294d99a44' 
  AND token = 'abrFEBk/b4WEVI7jYI0sqtAw/2EDlzc5NMJHrmOsQMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}