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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c4c5a6a5c0fb2c62a1850e79c62edccb4c5c8d54f8967fdc69da0955224203d' 
  AND token = 'k9m7nCEm1ayeq2vatroYbrG+XN8ZLfRJWroH1/V5Hss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}