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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1d74a2bdd22876e41eff010cec2851c7e3ac0c9b6e0740e06c7fe8367c18048' 
  AND token = '46xTafpoBImWRN5UoUXlVdJeY75UG0j4xlUzY4+cZvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}