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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9fb59af549b9f9898debf82f8ad3614b203eb805033492e435680ef9757d8884' 
  AND token = 'sTE7w5tiVoV+nn+ccXD0+E5IGMV5P33WzTUWT6mc5dM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}