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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d8574973c7975ce70b5d47d3be7c90bb7e1b0f528d7201b106c34886236ff08' 
  AND token = '09hh0D5n/kBUmUSQlhlJy3ejVtbRkixiwn63/DJbDQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}